Four Marvel was recorded in the ancient medicine book “Danxi’s Mastery of Medicine”, edited by Zhu Danxi in Yuan Dynasty and published in 1347 AD. The main action of the prescription is to clear Damp and Heat. Due to the combination of Huai Niu Xi (Radix Achyranthis Bidentatae) and Huai Niu Xi, it has the effect of strengthening the Kidneys, is dedicated to clear Dampness and Heat of the lower limbs and strengthening muscles and bones.

Clinically mainly used for prostatitis, swelling and pain of lower limb joints, numbness of legs, soreness of muscles and bones, atrophy of lower extremities, women’s morbid leucorrhoea, genital itching, men’s scrotum dampness, itching, and eczema of lower legs. It can also be used for lower extremity arteriosclerosis, thrombophlebitis, diabetic foot and other traditional Chinese medicine diseases belong to Damp–Heat in limbs or Lower Jiao.